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What is Subutex?

Subutex or buprenorphine sublingual is an opioid drug. Buprenorphine sublingual/oral (given under the tongue) is commonly used to treat opioid addiction. Subutex is indicated to treat opioid dependence and is preferred for induction. Subutex must be used as part of a complete treatment plan to include psychosocial support and counseling. You can buy Subutex online from us if you are addicted to opioids and experience withdrawal symptoms.

Other forms of buprenorphine are used for the treatment of moderate to severe pain. However, the sublingual form of buprenorphine is not for use as pain medicine.

Subutex (buprenorphine) sublingual tablet is an uncoated white oval flat beveled edged tablet, debossed with an alphanumeric word identifying the product and its strength on one side. This tablet contains buprenorphine HCl, a partial agonist at the mu-opioid receptor.

It is commonly available in two dosage strengths, 2 milligrams buprenorphine and 8 milligrams buprenorphine (as the free base, equivalent to 2.16 milligrams buprenorphine hydrochloride USP and 8.64 milligrams buprenorphine hydrochloride USP). Each Subutex tablet also contains cornstarch, povidone K30, lactose, mannitol, citric acid, sodium citrate, and magnesium stearate.

Warnings and precautions

Subutex tablets are not for use as pain medicine. Misuse may lead to addiction, overdose, or even death. Keep the Subutex medicine in a safe place where others can’t get to it.

Taking opioid medication during pregnancy can cause life-threatening withdrawal symptoms in the fetus. Hazardous side effects can occur if you use opioid medicine with alcohol or other medications that cause dizziness or slow breathing.

What should I do before taking Subutex?

You should not use Subutex (buprenorphine) if you are allergic to it or in case you have used another narcotic medication within the past four hours.

Inform the doctor if you have ever experienced:

  • sleep apnea, breathing problems;
  • methadone treatment;
  • liver disease (especially hepatitis B or C);
  • abnormal curvature of the spine affecting breathing;
  • enlarged prostate, urination problems;
  • kidney disease;
  • alcoholism, hallucinations, mental illness;
  • a head injury or brain tumor; or
  • problems with your adrenal gland, stomach, gallbladder, or thyroid.

If you use Subutex during pregnancy, the baby might become dependent on the medication. This may cause life-threatening symptoms of withdrawal in the fetus after it is born. Babies born dependent on habit-forming medicine may require medical treatment for several weeks. Subutex can pass into breast milk and cause dizziness and breathing problems in a nursing baby. Ask your doctor about any related health risks. Subutex is not approved for use by anyone aged below 18 years.

How should I take Subutex?

Follow the directions on your prescription label. Read all medication guides. Your doctor can occasionally change your dose. Use the drug precisely as directed. Do not use buprenorphine in larger amounts or for longer than required.

Subutex is usually taken only at the start of treatment for addiction. Most patients are later switched to another medication that contains buprenorphine (Suboxone, Bunavail, Sublocade, Zubsolv). You can receive your first doses of Subutex in a hospital or clinic setting until your condition gets better.

Never share the opioid drug with another person, especially someone with drug addiction or abuse history. Misuse may lead to addiction, overdose, or even death. Selling or giving away opioid medication is against the law. Use dry hands when handling the Subutex tablet. Place the Subutex tablet under your tongue and allow the Subutex tablet to dissolve with your mouth closed. Don’t chew the Subutex tablet or swallow the tablet whole.

If the doctor has prescribed more than 2 Subutex tablets per dose, place the correct number of Subutex tablets under your tongue at the same time and allow the tablets to dissolve completely. Don’t drink or eat anything until the film or tablet has completely dissolved in your mouth.

You might need frequent blood tests to check your liver function. Tell your surgeon ahead of time that you are using Subutex in case you need surgery. Never break or crush a buprenorphine tablet to inhale the powder or mix it into a liquid to inject the medicine into your vein. Doing so might result in death.

Any medical care provider who treats you must know that you are being treated for opioid addiction and taking Subutex. Ensure that your family members know how to provide this data if they need to speak for you during an emergency.

Don’t stop using Subutex suddenly, or you might have unpleasant withdrawal symptoms. Consult the doctor about how to stop using this drug safely.

Store the tablets at room temperature away from heat and moisture. Keep track of your drug. Subutex is a medication of abuse, and you must know if anyone is misusing your medicine or using it without a prescription.

Don’t keep leftover opioid drugs. Just one dose may cause death in someone using this medicine improperly or accidentally. Ask your pharmacist where to locate a medication take-back disposal program. If there is no such medication take-back program, flush the unused medication down the toilet.

What other medications will interact with buprenorphine sublingual?

You can have breathing problems or withdrawal symptoms if you stop or start taking certain other medicines with Subutex. Tell the doctor if you also use antifungal, antibiotic medication, seizure medication, heart or blood pressure medication, or medicine to treat hepatitis C or HIV.

Opioid medication can interact with many other medications and cause dangerous side effects or even death. Ensure your doctor knows if you also use:

  • medicines for irritable bowel syndrome, motion sickness, or overactive bladder;
  • bronchodilator asthma/COPD medication, cold or allergy medicines, or a diuretic (“water pill”);
  • a sedative like Valium- lorazepam, diazepam, alprazolam, Xanax, Versed, Klonopin, and others;
  • other narcotic medications–opioid pain medication or prescription cough medicine;
  • drugs that make you dizzy or slow your breathing–a sleeping pill, medicine to treat mood disorders or mental illness, muscle relaxer; or
  • medicines that affect serotonin levels in your body–a stimulant or medicine for depression, serious infections, Parkinson’s disease, migraine headaches, or nausea and vomiting

What are the side effects of Subutex?

These adverse reactions are possible while using Subutex- addiction, abuse, misuse, respiratory, CNS depression, neonatal opioid withdrawal syndrome, adrenal insufficiency, opioid withdrawal, hepatitis, hepatic events, hypersensitivity reactions, orthostatic hypotension, the elevation of cerebrospinal fluid pressure.

 

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